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《医学前沿（英文）》 2022年 第16卷 第5期 页码 808-814 doi: 10.1007/s11684-021-0878-x
关键词： epidermolysis bullosa LAMA3 COL7A1 KRT5 Chinese families
Xiaochen LIU, Hu LI, Yao CAI, Fan SONG, John-James WILSON, Wanzhi CAI
《农业科学与工程前沿（英文）》 2017年 第4卷 第3期 页码 358-365 doi: 10.15302/J-FASE-2017158
关键词： gene rearrangement mitochondrial genome Psocoptera Stenopsocidae TDRL model
Practice and principle of traditional Chinese medicine for the prevention and treatment of COVID-19
《医学前沿（英文）》 doi: 10.1007/s11684-023-1040-8
关键词： traditional Chinese medicine COVID-19 SARS-CoV-2 clinical evidence-based study mechanism integrated traditional Chinese and Western medicine
Jian Wang, Wen Zou
《医学前沿（英文）》 2011年 第5卷 第2期 页码 123-126 doi: 10.1007/s11684-011-0124-z
Individualized medicine, health medicine, and constitutional theory in Chinese medicine
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《医学前沿（英文）》 2012年 第6卷 第1期 页码 1-7 doi: 10.1007/s11684-012-0173-y
The patterns of modern science and changes in the medical model can result in the transformation of the current state of individualized and health medicines into being the primary trend in medical development. Chinese and Western medical systems are dissimilar in terms of value orientations, thinking style, and research directions because of their different historical and cultural backgrounds. Individualized treatment in modern medicine is mainly established based on individual genome information and the differences in mononucleotide polymorphi-sms. However, such treatment method is expensive, creates an uncertain genetic marker, and leads to different result interpretations, among other problems. The Chinese constitutional theory developed in the 1970s expresses the principle behind Chinese health medicine and individual treatment and provides the corresponding methods. The Chinese constitutional theory divides the constitution of the Chinese population into nine categories based on established classification criteria. It promotes the study of the relationship of each constitution to diseases and Chinese medicine preparation toward adjusting the constitution and preventing diseases. The theory also provides methods and tools for individualized treatment. Constitution identification shows the direction and provides the core technology for the evaluation of the health status. By combining the developments in modern biotechnology, new diagnostic techniques and treatment models of constitution-differentiation, disease-differentiation, and syndrome-differentiation can be established for the development of individualized Chinese medicine treatment and health medicine for the international medical community.
关键词： individualized medicine health medicine constitutional theory in Chinese medicine
Barriers and countermeasures in developing traditional Chinese medicine in Europe
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《医学前沿（英文）》 2016年 第10卷 第3期 页码 360-376 doi: 10.1007/s11684-016-0455-x
Traditional Chinese medicine (TCM) is one of the unique cultural treasures of Chinese; it represents a significant feature and prominent advantage of the healthcare cause in China. Data in this paper were from World Health Organization, Chinese Bureau of Statistics, China National Knowledge Infrastructure, and PubMed. In recent years, TCM has established a solid foundation in Europe, which made great strides in legislation, education, research, and international exchange, and has enjoyed a vast development space in the continent. Now, TCM is embracing unprecedented development opportunities in Europe. At the same time, the stiff international competition poses a grave threat to China’s TCM industry. With multiple cultural, legal, and institutional challenges, as well as talent shortages in the way, TCM is now facing many difficulties in Europe. To fully prepare and enact active and vigorous steps to seize opportunities, we should have a clear picture about the serious challenges hampering TCM development in Europe. The TCM development at overseas markets has shifted from a spontaneous trade activity into a national strategy spearheaded by the government and participated in by multiple stakeholders. We should make a systematic, comprehensive, and sustainable push in fields such as TCM therapy, healthcare, education, research, culture, and industry development. The ultimate goal is to bring TCMs to the global market and allow them to play a role in safeguarding public health along with modern medicines.
Named entity recognition for Chinese construction documents based on conditional random field
《工程管理前沿（英文）》 2023年 第10卷 第2期 页码 237-249 doi: 10.1007/s42524-021-0179-8
Zongyu John CHEN,
《医学前沿（英文）》 2010年 第4卷 第4期 页码 473-476 doi: 10.1007/s11684-010-0290-4
Traditional Chinese medicine in the new century
Jianxiang Liu, Zhu Chen
《医学前沿（英文）》 2011年 第5卷 第2期 页码 111-114 doi: 10.1007/s11684-011-0125-y
Ontological reconstruction of the clinical terminology of traditional Chinese medicine
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《医学前沿（英文）》 2014年 第8卷 第3期 页码 358-361 doi: 10.1007/s11684-014-0348-9
This study proposes the ontological reconstruction of the current clinical terminology of traditional Chinese medicine (TCM). It also provides an overview of preliminary work related to the said reconstruction, including the ontology-based analysis of TCM clinical terminology. We conclude that the ontological reconstruction of TCM clinical terminology provides a proper translation from the idealized organizational model to real-world implementation and to a formalized, shared, and knowledge-based framework.
关键词： ontology traditional Chinese medicine clinical terminology
Clinical research of traditional Chinese medicine in big data era
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《医学前沿（英文）》 2014年 第8卷 第3期 页码 321-327 doi: 10.1007/s11684-014-0370-y
With the advent of big data era, our thinking, technology and methodology are being transformed. Data-intensive scientific discovery based on big data, named “The Fourth Paradigm,” has become a new paradigm of scientific research. Along with the development and application of the Internet information technology in the field of healthcare, individual health records, clinical data of diagnosis and treatment, and genomic data have been accumulated dramatically, which generates big data in medical field for clinical research and assessment. With the support of big data, the defects and weakness may be overcome in the methodology of the conventional clinical evaluation based on sampling. Our research target shifts from the “causality inference” to “correlativity analysis.” This not only facilitates the evaluation of individualized treatment, disease prediction, prevention and prognosis, but also is suitable for the practice of preventive healthcare and symptom pattern differentiation for treatment in terms of traditional Chinese medicine (TCM), and for the post-marketing evaluation of Chinese patent medicines. To conduct clinical studies involved in big data in TCM domain, top level design is needed and should be performed orderly. The fundamental construction and innovation studies should be strengthened in the sections of data platform creation, data analysis technology and big-data professionals fostering and training.
关键词： big data traditional Chinese medicine clinical evaluation evidence based medicine
Jingqing Hu, Jie Qiao, Deying Kang, Baoyan Liu
《医学前沿（英文）》 2011年 第5卷 第2期 页码 203-207 doi: 10.1007/s11684-011-0138-6
《农业科学与工程前沿（英文）》 2022年 第9卷 第1期 页码 52-62 doi: 10.15302/J-FASE-2021402
Bradysia cellarum Frey (Diptera: Sciaridae) is an important subterranean pest and is especially damaging to Chinese chive. An effective and more environmentally safe method than pesticides is needed for its control. The efficacy of B. cellarum control, growth of Chinese chive and soil microbial diversity were investigated after uae of soil solarization to exterminate this insect pest. The results show that on the first day after soil solarization 100% control of B. cellarum was achieved. Growth of Chinese chive was lower in solarized plots than in control plots over the first 10 d after treatment. Chive growth in solarized plots increased subsequently to match that in the control plots. Moreover, the soil microbial community diversity in the treatment group decreased initially before gradually recovering. In addition, the abundance of beneficial microorganisms in the genus Bacillus and the phyla Proteobacteria, Chloroflexi and Firmicutes increased significantly. Soil solarization is therefore practical and worthy of promotion in Chinese chive-growing regions.
关键词： Bradysia cellarum / Chinese chive / control / soil microbes / soil solarization
Applications of dynamical complexity theory in traditional Chinese medicine
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《医学前沿（英文）》 2014年 第8卷 第3期 页码 279-284 doi: 10.1007/s11684-014-0367-6
Traditional Chinese medicine (TCM) has been gradually accepted by the world. Despite its widespread use in clinical settings, a major challenge in TCM is to study it scientifically. This difficulty arises from the fact that TCM views human body as a complex dynamical system, and focuses on the balance of the human body, both internally and with its external environment. As a result, conventional tools that are based on reductionist approach are not adequate. Methods that can quantify the dynamics of complex integrative systems may bring new insights and utilities about the clinical practice and evaluation of efficacy of TCM. The dynamical complexity theory recently proposed and its computational algorithm, Multiscale Entropy (MSE) analysis, are consistent with TCM concepts. This new system level analysis has been successfully applied to many health and disease related topics in medicine. We believe that there could be many promising applications of this dynamical complexity concept in TCM. In this article, we propose some promising applications and research areas that TCM practitioners and researchers can pursue.
关键词： traditional Chinese medicine Multiscale Entropy dynamical complexity system level applications
Developments in cancer prevention and treatment using traditional Chinese medicine
Hongsheng Lin, Jie Liu, Ying Zhang
《医学前沿（英文）》 2011年 第5卷 第2期 页码 127-133 doi: 10.1007/s11684-011-0137-7
标题 作者 时间 类型 操作
variants in LAMA3 and COL7A1 and recurrent variant in KRT5 underlying epidermolysis bullosa in five Chinesefamilies
期刊论文
Conserved gene arrangement in the mitochondrial genomes of barklouse families Stenopsocidae and Psocidae
Xiaochen LIU, Hu LI, Yao CAI, Fan SONG, John-James WILSON, Wanzhi CAI
期刊论文
Practice and principle of traditional Chinese medicine for the prevention and treatment of COVID-19
期刊论文
Practices, challenges, and opportunities: HIV/AIDS treatment with traditional Chinese medicine in China
Jian Wang, Wen Zou
期刊论文
Effectively cultivate the next generation of competent Chinese physicians: a perspective from a physiciantrained in both Chinese and US medical institutions
Zongyu John CHEN,
期刊论文
Analysis on the distinguishing features of traditional Chinese therapeutics and related statistical issues
Jingqing Hu, Jie Qiao, Deying Kang, Baoyan Liu
期刊论文
EFFECT OF SOLARIZATION TO KILL BRADYSIA CELLARUM ON CHINESE CHIVE GROWTH AND SOIL MICROBIAL DIVERSITY
期刊论文
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